Here's another interesting nugget:
"Hyperemesis Gravidarum – Severe Morning Sickness: Are Mitochondria Involved?"
It's a fascinating article, and the take-away is the suggestion of pre-conception supplementation with L-carnitine and CoQ10. The suggested dosage can be found at another article from the same site on mitochondrial dysfunction and cyclical vomiting syndrome:
- Co-enzyme Q10: Participants were treated with co-enzyme Q10 (ubiquinone) in liquid or gel capsule form (from a variety of brands) at a starting dose of 10 mg/kg/day, or 200 mg, divided twice a day, whichever is smaller.
- L-carnitine: Participants were treated with Carnitor brand or generics at a starting dose of 100 mg/kg/day divided BID, or 2 grams twice a day, whichever is smaller.
I think that this is a fascinating line of thought, and I am planning on adding both supplements to my regimen as of next month to see if there is a difference in our next pregnancy experience. (I will use this brand of L-carnitine (2 grams twice a day, for a daily total of 4 grams) and this brand of CoQ10 (100 mg twice a day, for a daily total of 200 mg).
Later edited to add: I began dosing with L-carnitine and CoQ10 on April 18, 2018. For the present, I am using half the dosage mentioned above, for the unfortunate reason that supplements are just so expensive. Hoping for good things!